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Quick Test may Speed Antibiotic Treatment Combat Drug Resistance

Described in Scientific Reports, NIST's prototype sensor provides results in less than an hour, much faster than conventional antimicrobial tests, which typically require days to grow colonies of bacterial cells. Delayed results from conventional tests allow dangerous infections to progress before effective treatments can be found and provides a time window

Mitochondria Drive Cell Survival in Times of Need

The research, published in Molecular Cell, builds on previous work by McGill professor Nahum Sonenberg, one of the senior authors of the new study. Cells in our body grow in size, mass and numbers through a process governed by a master regulator known as mTOR (Mechanistic Target of Rapamycin). Sonenberg discovered years

Ricin only Lethal in Combination with Sugar

The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made the headlines a number of times over the years, including the spectacular "umbrella murder" in London in the 1970s, or more recently the ricin letters addressed to

Human Skin Cells Transformed Directly Into Motor Neurons

In new research, scientists at Washington University School of Medicine in St. Louis have converted skin cells from healthy adults directly into motor neurons without going through a stem cell state. The technique makes it possible to study motor neurons of the human central nervous system in the lab. Unlike commonly

Zika Virus Kills Brain Cancer Stem Cells

The findings suggest that the lethal power of the virus -- known for infecting and killing cells in the brains of fetuses, causing babies to be born with tiny, misshapen heads -- could be directed at malignant cells in the brain. Doing so potentially could improve people's chances against a

Motorized Molecules Drill Through Cells

Researchers at Rice, Durham (U.K.) and North Carolina State universities demonstrated in lab tests how rotors in single-molecule nanomachines can be activated by ultraviolet light to spin at 2 to 3 million rotations per second and open membranes in cells. The researchers used motors based on work by Nobel laureate Bernard

Chemo-Boosting Drug Discovered for Leukemia

In a study published in Cancer Cell, researchers at the Francis Crick Institute, King's College London and Barts Cancer Institute discovered that acute myeloid leukemia (AML) - the most common acute leukemia affecting adults - causes bone marrow to 'leak' blood, preventing chemotherapy from being delivered properly. Drugs that reversed bone

New Source for Brain’s Development Discovered

The research, which appears in the journal Science, discovered that glia, a collection of non-neuronal cells that had long been regarded as passive support cells, in fact are vital to nerve-cell development in the brain. "The results lead us to revise the often neuro-centric view of brain development to now appreciate the

Repetitive Elements Shape Embryonic Chromatin Landscape

The researchers specifically investigated the role of so-called LINE1 (L1) elements, the most abundant retrotransposon family in mammals.* "We already knew L1 elements to be highly expressed in early embryogenesis and so we wanted to know if this transcription is important in the events taking place in the early embryo"

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