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Nerve Cells Gatekeepers Take Many Forms

Using sophisticated imaging and statistical methods, the scientists employed single-molecule FRET imaging techniques to establish a beachhead at the NMDA receptor gate that, when activated, allows ions to flow through the nerve cell's membrane. FRET stands for Förster resonance energy transfer. It is a way to use the light emitted by

Unique Gene Therapy Prevents, Reverses Multiple Sclerosis in Animal Model

By combining a brain-protein gene and an existing medication, the researchers were able to prevent the mouse version of multiple sclerosis. Likewise, the treatments produced near-complete remission in the animal models. The findings, which researchers said have significant potential for treating multiple sclerosis and other autoimmune disorders, are published in

The Pancreas Provides a Potential Drug Candidate for Brain Disease

In normal development, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which are required for myelination. OPCs will proliferate around the lesions of demyelination after injury and contribute to spontaneous remyelination, but the molecular mechanism of OPCs proliferation is not fully clarified. Osaka University Associate Professor Rieko Muramatsu focused on the

Patients Taking Opioids Prior to ACL Surgery More Likely to be on Pain Medications Longer

"With the ever-increasing opioid epidemic our nation is facing, understanding the risk factors for postoperative narcotic use could aid surgeons and healthcare systems in identifying patients who could benefit from a different pain management and counseling regimen than previously identified," said Chris A. Anthony, MD, lead researcher from the University

Link Between Vitamin D Treatment and Autism Prevention

Link between Vitamin D treatment and autism prevention Giving vitamin D supplements to mice during pregnancy prevents autism traits in their offspring, University of Queensland researchers have discovered. The discovery provides further evidence of the crucial role vitamin D plays in brain development, said lead researcher Professor Darryl Eyles, from UQ's Queensland

Vitamin D Deficiency Increases Risk of Chronic Headache

Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports. The Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD, analysed the serum vitamin D levels and occurrence of headache in approximately 2,600 men

Breakthrough in MS Treatment

In separate clinical trials, a drug called ocrelizumab has been shown to reduce new attacks in patients with relapsing remitting multiple sclerosis (MS), and new symptom progression in primary progressive MS. Three studies conducted by an international team of researchers, which included Amit Bar-Or and Douglas Arnold from the Montreal Neurological

Right Timing is Crucial in Life

The non-biting marine midge Clunio marinus lives along Europe's tide-shapen coasts, where precise timing is of existential importance: Reproduction and oviposition must occur when the tide is at its lowest. The tides, and therefore also low tide, are influenced by both the sun and the moon. To foresee the ideal

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