Described in Scientific Reports, NIST's prototype sensor provides results in less than an hour, much faster than conventional antimicrobial tests, which typically require days to grow colonies of bacterial cells. Delayed results from conventional tests allow dangerous infections to progress before effective treatments can be found and provides a time window
Tag: Lymphoma
Mitochondria Drive Cell Survival in Times of Need
The research, published in Molecular Cell, builds on previous work by McGill professor Nahum Sonenberg, one of the senior authors of the new study. Cells in our body grow in size, mass and numbers through a process governed by a master regulator known as mTOR (Mechanistic Target of Rapamycin). Sonenberg discovered years
Ricin only Lethal in Combination with Sugar
The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made the headlines a number of times over the years, including the spectacular "umbrella murder" in London in the 1970s, or more recently the ricin letters addressed to
Prototype Separates Components of Blood for Diagnostics
The system is optimized to sort out "exosomes," biological nanoparticles released from every type of cell in the body. Thought to play a large role in cell-to-cell communication and disease transmission, they have been objects of scientific curiosity since their discovery three decades ago. The miniscule size of exosomes, however, makes
Immune Cells Help Fat Deal With Environmental Challenges
The number of obese people as well as those suffering from type 2 diabetes is increasing worldwide. Both disorders are associated with metabolic changes including amplified inflammatory responses in adipose tissue. "Previous studies have indicated that immunosuppressive regulatory T-cells -- or Tregs for short -- play an important role in
A Tiny Device Offers Insights to How Cancer Spreads
Bacteria Responsible for Legionellosis Modulates the Host Cell Metabolism to its Advantage
L. pneumophila is a bacterial pathogen that causes Legionellosis -- a disease characterized by an acute pulmonary infection, which is often fatal when not treated promptly. In France, between 1200 and 1500 cases are identified each year, with mortality rates ranging from 5 to 15%. Researchers from the Institut Pasteur, CNRS and
Motorized Molecules Drill Through Cells
Researchers at Rice, Durham (U.K.) and North Carolina State universities demonstrated in lab tests how rotors in single-molecule nanomachines can be activated by ultraviolet light to spin at 2 to 3 million rotations per second and open membranes in cells. The researchers used motors based on work by Nobel laureate Bernard
Chemo-Boosting Drug Discovered for Leukemia
In a study published in Cancer Cell, researchers at the Francis Crick Institute, King's College London and Barts Cancer Institute discovered that acute myeloid leukemia (AML) - the most common acute leukemia affecting adults - causes bone marrow to 'leak' blood, preventing chemotherapy from being delivered properly. Drugs that reversed bone
New Antibodies Target Protein Structures Common to Several Neurological diseases
This is the finding of a study led by researchers from NYU School of Medicine and published online August 29 in Scientific Reports. The new study is based on decades of work arguing that the contribution to disease of key proteins -- amyloid beta and tau in Alzheimer's, alpha-synuclein in Parkinson's, and