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Sensor for the Most Important Human Cancer Gene

Cancer is caused by changes in the human genome. Mutations in oncogenes and in tumor suppressor genes accumulate unrecognized over time and lead to uncontrolled cell proliferation eventually. In 50% of all human tumors the tumor suppressor gene TP53 is no longer functional being the most frequently mutated cancer gene.

Engineering Non-immune Cells to Kill Cancer Cells

But researchers have recently used T-cells engineered in the laboratory to combat tumours. Modified to include additional functions, these immune cells can hunt down and kill cancer cells. Unfortunately, however, such immune cell therapies can have significant side-effects. On top of that, the production of modified T-cells is technically challenging.

First Draft cell Atlas of the Small Intestine

This census, published in Nature, comprises a first-draft atlas of the small intestine's cellular composition, providing a reference for studying the biology of a host of conditions affecting or involving the gut, such as inflammatory bowel disease, cancers of the small intestine, celiac disease, and food allergies. The study also enhances

Newly discovered microRNA regulates mobility of tumor cells

During an embryo's development, epithelial cells can break away from the cell cluster, modify their cell type-specific properties, and migrate into other regions to form the desired structures there. This process, which is known as an epithelial-mesenchymal transition (EMT), is reversible and can also proceed in the direction from mesenchymal

Single Cell Diagnostics for Breast Cancer

"Breast tumors are moving targets because they are really versatile," says Jun-Lin Guan, Francis Brunning Professor and Chair of the Department of Cancer at the University of Cincinnati College of Medicine and member of the Cincinnati Cancer Center and UC Cancer Institute, who co-authored the paper with postdoctoral fellow Syn

Zinc Can Halt the Growth of Cancer Cells, study Says

Previous studies had shown that zinc is essential for maintaining human health and protects the esophagus from cancer. However, it has never been fully understood why zinc has the ability to prevent cancer in the esophagus. In this study, a team led by Zui Pan, an associate professor of nursing

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