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New Methods Reveal the Biomechanics of Blood Clotting

The extensive results are published in two separate studies, in the Proceedings of the National Academy of Sciences (PNAS) and in Nature Methods. "We show conclusively that, in order to activate clotting, the cell needs a targeted force of a magnitude of just a few piconewtons -- or a force about a billion times

Cases of Unexplained Anaphylaxis Linked to Red Meat Allergy

As the researchers describe in their article published in Allergy, six of the 70 study participants evaluated for unexplained frequent anaphylaxis tested positive for an allergy to galactose-a-1,3-galactose, or alpha-gal, a sugar molecule found in beef, pork, lamb and other red meats. The six adult male participants all had IgE antibodies

Gobbling Your Food may Harm Your Waistline and Heart

Metabolic syndrome occurs when someone has any of three risk factors that include abdominal obesity, high fasting blood sugar, high blood pressure, high triglycerides and/or low HDL cholesterol, said Japanese researchers. The researchers evaluated 642 men and 441 women, average age 51.2 years, who did not have metabolic syndrome in 2008.

Diabetes New Insulin Sensitizers Discovered

A new study, led by researchers at Columbia University Medical Center, indicates that it may be possible to improve insulin sensitivity while avoiding these adverse effects. The findings were published online in Cell. Insulin, a hormone made in the pancreas, signals cells to grab glucose out of the bloodstream and use it

Nerve Cells Gatekeepers Take Many Forms

Using sophisticated imaging and statistical methods, the scientists employed single-molecule FRET imaging techniques to establish a beachhead at the NMDA receptor gate that, when activated, allows ions to flow through the nerve cell's membrane. FRET stands for Förster resonance energy transfer. It is a way to use the light emitted by

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