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Driving Drug Resistance out of Fungi

Microbiologists are facing tremendous difficulties in their quest to fight C. albicans' drug resistance and biofilm formation. Each C. albicans microbe is a "diploid" organism, as it usually contains two copies of its entire genome and of all the genes encoded within. However, to understand the role that a specific gene plays, researchers

Scientists Develop New Theory of Molecular Evolution

"Molecules are the basis of all life and we wanted to find out why molecules evolve the way they do," said study co-author David Pollock, PhD, professor of biochemistry and molecular genetics at the CU School of Medicine. Pollock and fellow author Richard Goldstein, Ph.D., professor of infection and immunity at

Genes are Controlled by Nano Footballs Scientists Discover

By placing tiny glowing probes on transcription factors -- special chemicals inside cells which control whether a gene is switched 'on' or 'off' -- researchers gained a remarkable new insight into the way in which genes are controlled. Crucially, they discovered that transcription factors operate not as single molecules as was

New Genetic Syndrome Predisposes the Body to Cancer

A research led by Jordi Surrallés, professor of the Department of Genetics and Microbiology at the Universitat Autònoma de Barcelona, director of the Genetics Unit at the Hospital de la Santa Creu i Sant Pau and lead researcher at the Centre for Biomedical Network Research on Rare Diseases (CIBERER), has

Multifunctional Nano Sized Drug Carriers Based on Reactive Polypept(o)ides

In cooperation with researchers from the University of Tokyo and Gutenberg Research Awardee Prof. Kazunori Kataoka, Chemists from Mainz have been able to demonstrate that reactive polypept(o)ides constitute ideal building blocks to control morphology and function of carrier systems in a simple but precise manner. Polypept(o)ides (polysarcosine-block-polypeptide copolymers) have emerged

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