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Alcohol Damages DNA and Increases Cancer Risk

Much previous research looking at the precise ways in which alcohol causes cancer has been done in cell cultures. But in this study, researchers have used mice to show how alcohol exposure leads to permanent genetic damage. Scientists at the MRC Laboratory of Molecular Biology, Cambridge, gave diluted alcohol, chemically known

Potential Path to Repair MS-Damaged Nerves

Multiple sclerosis is an autoimmune, neurodegenerative disease, characterized by distinct disabilities affecting walking, vision, and cognition, to name a few. MS patients differ markedly from each other regarding which disability affects them the most. Inflammation strips the myelin coating from nerve cell extensions, called axons, and connections at the ends

Driving Drug Resistance out of Fungi

Microbiologists are facing tremendous difficulties in their quest to fight C. albicans' drug resistance and biofilm formation. Each C. albicans microbe is a "diploid" organism, as it usually contains two copies of its entire genome and of all the genes encoded within. However, to understand the role that a specific gene plays, researchers

Scientists Develop New Theory of Molecular Evolution

"Molecules are the basis of all life and we wanted to find out why molecules evolve the way they do," said study co-author David Pollock, PhD, professor of biochemistry and molecular genetics at the CU School of Medicine. Pollock and fellow author Richard Goldstein, Ph.D., professor of infection and immunity at

Genes are Controlled by Nano Footballs Scientists Discover

By placing tiny glowing probes on transcription factors -- special chemicals inside cells which control whether a gene is switched 'on' or 'off' -- researchers gained a remarkable new insight into the way in which genes are controlled. Crucially, they discovered that transcription factors operate not as single molecules as was

New Genetic Syndrome Predisposes the Body to Cancer

A research led by Jordi Surrallés, professor of the Department of Genetics and Microbiology at the Universitat Autònoma de Barcelona, director of the Genetics Unit at the Hospital de la Santa Creu i Sant Pau and lead researcher at the Centre for Biomedical Network Research on Rare Diseases (CIBERER), has

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