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Unique Gene Therapy Prevents, Reverses Multiple Sclerosis in Animal Model

By combining a brain-protein gene and an existing medication, the researchers were able to prevent the mouse version of multiple sclerosis. Likewise, the treatments produced near-complete remission in the animal models. The findings, which researchers said have significant potential for treating multiple sclerosis and other autoimmune disorders, are published in

Eye movements reveal temporal Expectation Deficits in ADHD

Emerging evidence shows that small involuntary eye movements (saccades and microsaccades) are a promising new tool for shedding light on the hidden workings of mental processes like attention and anticipation, cognitive processes that are often impaired in individuals with ADHD. The new study suggests that carefully tracking eye movements offers a

Human Skin Cells Transformed Directly Into Motor Neurons

In new research, scientists at Washington University School of Medicine in St. Louis have converted skin cells from healthy adults directly into motor neurons without going through a stem cell state. The technique makes it possible to study motor neurons of the human central nervous system in the lab. Unlike commonly

Scientists Discover Brain Area which can be Targeted for Treatment in Patients with Schizophrenia Who ‘Hear Voices’

"This is the first controlled trial to precisely determine an anatomically defined brain area where high frequency magnetic pulses can improve the hearing of voices," said lead researcher, Professor Sonia Dollfus (University of Caen, CHU, France). Schizophrenia is a serious long-term mental health problem. People with schizophrenia experience a range of

The Pancreas Provides a Potential Drug Candidate for Brain Disease

In normal development, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which are required for myelination. OPCs will proliferate around the lesions of demyelination after injury and contribute to spontaneous remyelination, but the molecular mechanism of OPCs proliferation is not fully clarified. Osaka University Associate Professor Rieko Muramatsu focused on the

New Drug May Treat and Limit Progression of Parkinson’s Disease

Symptoms of Parkinson's disease are commonly managed using a selective dopamine receptor agonists. While these drugs are useful in early-stage Parkinson's, they tend to lose efficacy in later disease stages. As important, currently marketed drugs do not appear to modify disease progression. A research team including Binghamton University psychology professor

Childhood Psychiatric Disorders Increase Risk for Later Adult Addiction

The team, led by researchers from the Child Study group at the Vrije Universiteit in Amsterdam and Accare, the Center for Child and Adolescent Psychiatry at the University Medical Center Groningen, the Netherlands, found that individuals diagnosed in childhood with attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD)/conduct disorder (CD), and

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