The disorder can therefore lead to serious brain damage and even death in the worst cases. A team at the University of Geneva (UNIGE), Switzerland, supported by the Swiss National Science Foundation (SNSF) has succeeded in precisely describing the effects of a frequent genetic mutation in cases of congenital hyperinsulinism.
The research, which appears in the journal Science, discovered that glia, a collection of non-neuronal cells that had long been regarded as passive support cells, in fact are vital to nerve-cell development in the brain. "The results lead us to revise the often neuro-centric view of brain development to now appreciate the
In normal development, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which are required for myelination. OPCs will proliferate around the lesions of demyelination after injury and contribute to spontaneous remyelination, but the molecular mechanism of OPCs proliferation is not fully clarified. Osaka University Associate Professor Rieko Muramatsu focused on the
This picture of the basic nature of Fragile X has been reinforced by a series of studies reported in a paper titled "Fragile X Mental Retardation Protein Requirements in Activity Dependent Critical Period Neural Circuit Refinement" published Aug. 7 in the journal Current Biology. The research was conducted by a team of
In order to further advance current state of knowledge on the positive influence of physical activity on the brain, gerontologists and sports physicians at Goethe University Frankfurt have examined the effects of regular exercise on brain metabolism and memory of 60 participants aged between 65 and 85 in a randomised
"Feelings of empathy are virtues we want to cultivate personally and in society," says first author Yoni Ashar (@YoniAshar), a graduate student in the lab of Tor D. Wager (@torwager), professor of neuroscience at the University of Colorado, Boulder. "Understanding these emotions could open the doors to increasing empathy and
Until recently, the blood supply to the brain (cerebral blood flow or CBF) was thought to be involuntarily regulated by the body and relatively unaffected by changes in the blood pressure caused by exercise or exertion. The NMHU research team and others previously found that the foot's impact during running
When a person loses a hand to amputation, nerves that control sensation and movement are severed, causing dramatic changes in areas of the brain that controlled these functions. As a result, areas of the brain devoted to the missing hand take on other functions. Now, researchers from the University of