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‘Missing Link’ Explains How Viruses Trigger Immunity

The research team demonstrated a protein called SIDT2 was crucial for cells to detect viral components in their environment, and initiate an immune response to reduce the virus' spread. As well as being an important part of the intricate 'arms race' between viruses and our immune system, the finding could inform

Protein that Extends Life of Yeast Cells

For about one hundred years it has been known that nutrient restriction and moderate stress can significantly prolong life. The researchers led by Prof. Mihaela Zavolan and Prof. Anne Spang, both at the Biozentrum of the University of Basel, have discovered how the transcription factor Gcn4, a protein that regulates

Immature Cells Grow up to be Red Blood Cells

In order to make as much room as possible for the oxygen-carrying protein hemoglobin, pretty much everything else inside these precursor red blood cells -- nucleus, mitochondria, ribosomes and more -- gets purged. Jam-packing red blood cells with hemoglobin is essential. Doing so ensures that all the body's tissues and

Sweet Sugar Coated Probe Yields Better Acid Test

Abnormal pH -- in particular, abnormally low, acid pH -- is a marker for maladies ranging from cystic fibrosis, stroke and rheumatoid arthritis to cancer and Alzheimer's. Now, Michigan Technological University chemist Haiying Liu has developed new tools that could make it much easier to detect low pH in living

Miniature Human Hearts Created from Rat Hearts

For years, researchers have used the Langendorff method to remove the heart from an animal in order to introduce fluid through the aorta, the body's largest vessel, then into the artery network of a heart. This method is also used to deliver solutions that strip away cells from the rat

Switchable Dna Mini-Machines Store Information

The arrays' structures look like accordion-style retractable security gates. Extending or contracting one unit pushes nearby units to change shape as well, working like a domino cascade whose tiles are connected. The arrays' units get their stability from the energy gained when DNA double helices stack up. To be stable, the

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