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New Term for Role of Microbiota in Neurodegeneration Proposed

University of Louisville neurology professor Robert P. Friedland, M.D., and Matthew R. Chapman, Ph.D., professor at the University of Michigan, have proposed a new term to describe an interaction between gut microbiota and the brain in an article released today in PLOS Pathogens. Friedland and Chapman propose the term "mapranosis" for the

Cases of Unexplained Anaphylaxis Linked to Red Meat Allergy

As the researchers describe in their article published in Allergy, six of the 70 study participants evaluated for unexplained frequent anaphylaxis tested positive for an allergy to galactose-a-1,3-galactose, or alpha-gal, a sugar molecule found in beef, pork, lamb and other red meats. The six adult male participants all had IgE antibodies

Seemingly Acute Viral Infections Can Persist

New findings from the University of Pennsylvania suggest a mechanism that may explain how viruses can linger. Products of viral infection called defective viral genomes, DVGs for short, which have been known to be involved in triggering an immune response, can also kick off a molecular pathway that keeps infected

A Tubular Structure to Stop Cell Growth

Some of the treasures of Easter Island are invisible. In the 1960s, researchers discovered a bacterium that produces a compound with potent anti-fungal properties. They called it rapamycin, from the island's native name Rapa Nui. Although evolutionarily distant, fungi and mammals share much of the basic biochemistry that drives cellular

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