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Brain Cells Die in Alzheimer’s and FTD

In the brain, LSD1 (lysine specific histone demethylase 1) maintains silence among genes that are supposed to be turned off. When the researchers engineered mice that have the LSD1 gene snipped out in adulthood, the mice became cognitively impaired and paralyzed. Plenty of neurons were dying in the brains of

New Hope for ‘Bubble Baby Disease’

Research led by the University of Hong Kong has resulted in a new testing regime that could speed up the diagnosis of SCID, allowing more infants to receive life-saving treatment within a critical timeframe. For the best chance of survival, infants with SCID should be treated as soon after birth as

New Drug May Treat and Limit Progression of Parkinson’s Disease

Symptoms of Parkinson's disease are commonly managed using a selective dopamine receptor agonists. While these drugs are useful in early-stage Parkinson's, they tend to lose efficacy in later disease stages. As important, currently marketed drugs do not appear to modify disease progression. A research team including Binghamton University psychology professor

New Treatment Options for Non-Alcoholic Fatty Liver Disease

The composition of the diet and the degree of physical activity are the main drivers determining the risk to develop non-alcoholic fatty liver disease in addition to genetic predisposition. A subgroup of patients with NAFLD progresses to the inflammatory subtype of the disease called non-alcoholic steatohepatitis (NASH). NASH promotes collagen

Sleep Disorders May Increase Cognitive Problems Particularly in those at Risk for Alzheimer’s

In "Greater Cognitive Deficits with Sleep-Disordered Breathing among Individuals with Genetic Susceptibility to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis," researchers report that study participants carrying the apolipoprotein ?-4 (APOE-?4) allele showed greater cognitive deficits with the various indices of sleep-disordered breathing compared to those without the allele. APOE is a

The Brain’s Rejuvenating Cells

The brain is a fragile and unique organ that has its own specially tailored immune system, separate from the rest of the body. The primary role of the brain's immune cells, called microglia, is to recognize, disassemble, and dispose of various substances that do not function properly in the brain,

Air Pollution May Lead to Dementia in Older Women

Tiny air pollution particles -- the type that mainly comes from power plants and automobiles -- may greatly increase the chance of dementia, including Alzheimer's disease, according to USC-led research. Scientists and engineers found that older women who live in places with fine particulate matter exceeding the U.S. Environmental Protection Agency's

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