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Diabetes Drug ‘Significantly Reverses Memory Loss’ in Mice with Alzheimer’s

The research, published in Brain Research, could bring substantial improvements in the treatment of Alzheimer's disease through the use of a drug originally created to treat type 2 diabetes. Lead researcher Professor Christian Holscher of Lancaster University in the UK said the novel treatment "holds clear promise of being developed into a

Alcohol Damages DNA and Increases Cancer Risk

Much previous research looking at the precise ways in which alcohol causes cancer has been done in cell cultures. But in this study, researchers have used mice to show how alcohol exposure leads to permanent genetic damage. Scientists at the MRC Laboratory of Molecular Biology, Cambridge, gave diluted alcohol, chemically known

New Patch Aims to Turn Energy Storing Fats into Energy-Burning Fats

It combines a new way to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat. This innovative approach developed by scientists from Nanyang Technological University, Singapore (NTU Singapore) reduced weight gain in mice on a high fat diet and

Autism Therapy Social Behavior Restored Via Brain Stimulation

The research from the O'Donnell Brain Institute provides the first evidence that a specific part of the cerebellum, a region near the brain stem that has long been thought to only have roles in coordinating movement, is critical for autistic behaviors. It also establishes a more accessible target for brain

Dopamine Levels Fall During Migraine Attacks, Brain Scans Show

This could help scientists better understand dopamine-based therapies for migraines as well as a patient's behavior during an attack. The connection between dopamine and migraines has long been a poorly understood therapeutic and research area, says Alex DaSilva, assistant professor at the U-M School of Dentistry and Center for Human Growth

Harnessing sperm to treat gynecological Diseases

Creating an effective way to target cancer cells with drugs is challenging on multiple fronts. For example, the drugs don't always travel deeply enough through tissues, and they can get diluted in body fluids or sidetracked and taken up by healthy organs. To get around these issues, scientists have turned

Deep brain stimulation: Improving outcomes in the treatment of movement disorders

For the first time, researchers from the Movement Disorders Unit of the Department of Neurology have shown that both symptom severity and the clinical outcomes achieved through deep brain stimulation (DBS) are directly linked to a specific pattern of brain activity, which is found in patients with isolated dystonia. In

Rate and Risk of Head Injury in Mixed Martial Arts Remain Unknown

Researchers at St. Michael's Hospital reviewed 18 studies involving 7,587 patients, examining head injuries in MMA fighting published between 1990 and 2016. Of the studies included in the review, published online in the journal Trauma, there was no consistent definition of head injury, concussion or traumatic brain injury, or consistent protocol for

Taking Folic Acid in Late Pregnancy may Increase Childhood Allergy Risk

Folic acid, a type of B vitamin, has been shown to prevent defects in the neural tube -- the precursor to the central nervous system -- in a developing fetus. The neural tube develops in the first month of pregnancy; medical professionals typically recommend women take a folic acid supplement

Designer Nanoparticles Destroy a Broad Array of Viruses

Now, an international group of researchers including UIC professor of chemistry Petr Kral, have designed new anti-viral nanoparticles that bind to a range of viruses, including herpes simplex virus, human papillomavirus, respiratory syncytial virus and Dengue and Lentiviruses. Unlike other broad-spectrum antivirals, which simply prevent viruses from infecting cells, the

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