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Old World Monkeys Could be Key to a New, Powerful Rheumatoid Arthritis Therapy

"RTD-1 is the prototype of a family of small cyclic peptides (θ-defensins), the only circular proteins in the animal kingdom," says study author Michael Selsted, MD, PhD, chair and professor of pathology at the Keck School. "Previous studies have shown that RTD-1 modulates lethal inflammation in animal models of infection,

Study Raises Possibility of Naturally Acquired Immunity Against Zika Virus

New research in PLOS Pathogens on Nov. 16, performed in mice, shows women who develop symptom-free Zika infections may be able to acquire immunity that would protect them from future infections and their offspring in a future pregnancy. The study was led by investigators at the Cincinnati Children's Perinatal Institute. During their study

Noninvasive brain imaging shows readiness of trainees to perform Operations

The study, led by Suvranu De, the J. Erik Jonsson '22 Distinguished Professor of Engineering and head of the Department of Mechanical, Aerospace, and Nuclear Engineering; and Xavier Intes, professor in the Department of Biomedical Engineering and director of the Functional & Molecular Optical Imaging Laboratory; along with Arun Nemani,

Consuming Nuts Strengthens Brainwave Function

In the study titled "Nuts and brain: Effects of eating nuts on changing electroencephalograph brainwaves," researchers found that some nuts stimulated some brain frequencies more than others. Pistachios, for instance, produced the greatest gamma wave response, which is critical for enhancing cognitive processing, information retention, learning, perception and rapid eye

Kill Switches for Engineered Microbes Gone Rogue

Past efforts at Harvard's Wyss Institute for Biologically Inspired Engineering led by Core Faculty members Pamela Silver and James Collins have created "kill switches" in bacteria that cause them to commit suicide in laboratory conditions when they are not wanted anymore. "We needed to take our previous work further and

Ancient Enzyme Could Boost Power of Liquid Biopsies to Detect and Profile Cancers

Alan Lambowitz, a professor in the Institute for Cellular and Molecular Biology and the Department of Molecular Biosciences, and his team are studying an ancient enzyme in bacteria that can be used to detect bits of genetic material shed by cancer or other diseased cells into a patient's bloodstream. Many current

Gobbling Your Food may Harm Your Waistline and Heart

Metabolic syndrome occurs when someone has any of three risk factors that include abdominal obesity, high fasting blood sugar, high blood pressure, high triglycerides and/or low HDL cholesterol, said Japanese researchers. The researchers evaluated 642 men and 441 women, average age 51.2 years, who did not have metabolic syndrome in 2008.

A delicate Crossing Controller Developed to Open the Blood-Brain Barrier with Precision

"We want to be able to monitor our ability to open the blood-brain barrier in real-time by listening to echoes -- this could give us immediate information on the stability of the microbubbles oscillations and give us fast, real-time control and analysis," said lead author Tao Sun, a PhD candidate

Gut Microbes can Protect Against High Blood Pressure

The MIT team, working with researchers in Germany, found that in both mice and humans, a high-salt diet shrinks the population of a certain type of beneficial bacteria. As a result, pro-inflammatory immune cells called Th-17 cells grow in number. These immune cells have been linked with high blood pressure,

Eating Regular Variety of Nuts Associated with Lower Risk of Heart Disease

Recently, dietary recommendations have shifted toward diets including higher quantities of plant-based foods over animal-based foods, with most dietary patterns including nuts because of their association with reduced cardiovascular risk factors and unique nutritional composition. While many past studies focused on nut consumption as a whole, researchers in this study also

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